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冯世秀
博士,副研究员/高级工程师

教育经历

  • 2008-2011年,中国科学院华南植物园,博士
  • 2010-2011年,英属哥伦比亚大学,访问学者
  • 2005-2008年,中国科学院华南植物园,硕士
  • 2001-2005年,西北农林科技大学,学士

工作经历

  • 2013年至今,深圳市仙湖植物园,高级工程师
  • 2011-2013年,深圳市仙湖植物园,助理研究员

研究领域

  • 药用植物、资源收集、化学药理、开发利用

荣誉及获奖

  • 2019年获得深圳市科技进步二等奖,获奖项目为“华南滨海城市绿地盐化土壤修复关键技术及应用”,排名第四。
  • 2019年认定为深圳市高层次人才。

主持和承担的研究课题

  • 1. 国家自然科学基金青年基金,基于Hsp90抑制的黄根四氢蒽醌衍生物抗肿瘤作用与构效关系研究,编号:31500284,执行期限:2016.01-2018.12。
  • 2. 深圳市科技创新委基础研究项目,基于tetrahydroanthraquinone类天然产物分子探针研发高效低毒抗肿瘤先导化合物,编号:JCYJ20140905095624296,执行期限:2015.01-2016.12。
  • 3. 深圳市科技创新委基础研究项目,抗真菌C-27甾体皂苷的发现及构效关系研究,编号:JCYJ20120615153136998,执行期限:2012.11-2014.08。

代表性论著

  • [1]Feng Shixiu*, Weiyi Wang*. Bioactivities and structure-activity relationships of natural tetrahydroanthraquinone compounds: a review. Frontiers in Pharmacology. May2020, Volume 11, Article 799.
  • [2]Feng Shixiu*, Wang Zhenzhen, Zhang Min, Zhu Xiaohui, Ren Zhanjun. HG30, a tetrahydroanthraquinone compound isolated from the roots of prismatomeris connate, induces apoptosis in human non-small cell lung cancer cells. Biomedicine & Pharmacotherapy, 2018, 100: 124-131.
  • [3]Shixiu Feng, Bo Yi*, Min Zhang, Jing Xu, Hai Lin, Wentong Xu. Iridoid glycosides from Callicarpa nudiflora Hook.. Natural Product Research 2017, 31(2):181-189.
  • [4]Feng Shixiu*, Zhang Min, Jing Xu, Hu Yinmin. Prisconnataones A, a cytotoxic naphthoquinone from Prismatomeris connate, suppresses the proliferation of human laryngocarcinoma Hep-2 cells, in vitro. Natural Product Research. 2016, 30(24): 2840-2844.
  • [5]Shixiu Feng, Yuyang Jiang, Jiong Li, Shengxiang Qiu and Tao Chen*. A new bixanthone derivative from the bark of Garcinia oblongifolia. Natural Product Research, 2014, 28: 81-85.
  • [6]Xiaoqian Zhang, Jing Shi, Shixiu Feng, Xue Lin, Liping Tian. Two new phenolic glycosides from the seeds of Citrullus lanatus. Natural Product Research, 2020, 34(3): 398-404.
  • [7]Wenyu Ma, Leping Ma, Bo Yi, Min Zhang, Shixiu Feng*, Liping Tian*. Antidiabetic activity of Callicarpa nudiflora extract in type 2 diabetic rats via activation of the AMPK-ACC pathway. Asian Pacific Journal of Tropical Biomedicine. 2019, 9(11): 456-466.
  • [8]Yudui Xia, Xia Liu, Chunlin Zou, Shixiu Feng, Hongwei Guo, Yeguo Yang, Yong Lei, Jian Zhang, Yi Lu. Garcinone C exerts antitumor activity by modulating the expression of ATR/Stat3/4E-BP1 in nasopharyngeal carcinoma cells. Oncology Reports, 2018,39: 1485-1493.
  • [9]Yuanyuan Zhan, Jinhui Wang, Xian Tian, Shixiu Feng, Lin Xue, Liping Tian. Journal of Ethnopharmacology. 2016, 193: 531-537.
  • [10]Chunxiang Wang, Xiao, Shixiu Feng, Qiunong Guan, Xiaoping Zhang, Caigan Du*, Yingtong Di, Tao Chen*. Seven new tetrahydroanthraquinones from the root of Prismatomeris connata and their cytotoxicity against lung tumor cell growth. Molecules, 2015, 20(12):22565-22577.
  • [11]Jing Xu, Shixiu Feng, Qi Wang, Min Zhang, Cunli Zhang*. A new flavonoid glycoside from the rhizo mes and roots of Smilax scobinicaulis. Natural Product Research. 2014, 28(8):517-512.
  • [12]Jing Xu, Shixiu Feng, Qi Wang, Yingli Cao, Miao Sun and Cunli Zhang*. Four new furostanol saponins from the rhizomes and roots of Smilax scobinicaulis. Molecules, 2014, 19: 20975-20987.
  • [13]Junmin Shi, Huijuan Huang, Shengxiang Qiu, Shixiu Feng, Xu-e Li. Molecules. 2014, 19: 1422-1431.
  • [14]Cunli Zhang, Shixiu Feng, Qi Wang, Ping Wang, Jing Xu, Tao Chen. Chemistry of Natural Compounds. 2014, 50(2).

专利

  • 1.化合物garcibixanthone A及其制备方法和应用,专利号:ZL. 202010395314.1,授权日期:2020年8月14日。
  • 2.一种抗肿瘤裸花紫珠提取物及其制备方法和用途, 专利号:ZL. 201310724691.5, 授权日期2017年10月20日。
  • 3.双酮类化合物FLBG-1108或者其药用盐在制备抗癌药物中的应用,专利号:ZL.201310093728.9,授权日期:2014年7月16日。

联系方式

  • 邮件:fengshixiu@szbg.ac.cn; 电话: 0755-25702889